(选自United KingdomNature杂志,2012年四月29日出版)聚胺对“抗酶”的调节效果机制:
& VIEWS———————-Ageing: Longevity hits a roadblock
pp410-411Increased expression of sirtuin proteins has been shown to
enhance lifespan in several organisms. New data indicate that some of
the reported effects may have been due to confounding factors in
experimental design. Here, experts discuss the significance of these
data for research into ageing. See Letter p.482David B.Lombard, Scott
D.Pletcher, Carles Canto and Johan
science: Slippery when wetted pp412-413The slick interior of the pitcher
plant has inspired a slippery material possessing self-lubricating,
self-cleaning and self-healing properties. The secret is to infuse a
porous material with a liquid that repels oils and water. See Letter
biology: A yeast for all reasons pp413-414Scientists have begun to
overhaul a yeast’s genome to make it more stable, engineerable and
evolvable. Remarkably, the part-natural, part-synthetic yeast cells
function and reproduce without obvious ill effects. See Letter
p.471Peter J.Enyeart and Andrew
physics: Single electrons take the bus p414Single-electron circuitry is
a promising route for quantum information processing. The demonstration
of single-electron transfer between two distant quantum dots brings this
technology a step closer. See Letters p.435 & p.439Takis
Endless variation most beautiful pp415-416The genetic basis of traits
can be understood by comparing the DNA of varieties of the same species.
The genomes of many varieties of a model plant organism have now been
sequenced, and the results are revelatory. See Article p.419Michael
Precisely tuned antibodies nab HIV pp416-417Newly discovered
neutralizing antibodies that target sites on the envelope proteins of
HIV-1 provide a window on how some of the most powerful of these
antibodies acquire their potency and breadth of activity. See Letter
p.466Paul R.Clapham and Shan
reference genomes and transcriptomes for Arabidopsis thaliana
pp419-423Xiangchao Gan et al.doi:10.1038/nature10414Abstract:

elements mediate control of VJ recombination pp424-430Chunguang Guo et

close nuclear black-hole pair in the spiral galaxy NGC 3393
pp431-434G.Fabbiano, Junfeng Wang, M.Elvis and

surfing on a sound wave as a platform for quantum optics with flying
electrons pp435-438Sylvain Hermelin et

single-electron transfer between distant quantum dots
pp439-442R.P.G.McNeil et al.doi:10.1038/nature10444Abstract:

self-repairing slippery surfaces with pressure-stable omniphobicity
pp443-447Tak-Sing Wong et al.doi:10.1038/nature10447Abstract:

iron-rich conditions in the mid-Proterozoic ocean pp448-451Noah
J.Planavsky et al.doi:10.1038/nature10327Abstract:

reveals deep molluscan relationships pp452-456Kevin M.Kocot et

resistance is ancient pp457-461Vanessa M.D’Costa et

for several waves of global transmission in the seventh cholera pandemic
pp462-465Ankur Mutreja et al.doi:10.1038/nature10392Abstract:
neutralization coverage of HIV by multiple highly potent antibodies
pp466-470Laura M.Walker et al.doi:10.1038/nature10373Abstract:

chromosome arms function in yeast and generate phenotypic diversity by
design pp471-476Jessica S.Dymond et al.doi:10.1038/nature10403Abstract:

actions of a non-agonist PPARγ ligand blocking Cdk5-mediated
phosphorylation pp477-481Jang Hyun Choi et

of effects of Sir2 overexpression on lifespan in C. elegans and
Drosophila pp482-485Camilla Burnett et

of the RNA-guided surveillance complex from a bacterial immune system
pp486-489Blake Wiedenheft et al.doi:10.1038/nature10402Abstract:

sensing by nascent ornithine decarboxylase antizyme stimulates decoding
of its mRNA pp490-494Leo Kurian, R.Palanimurugan, Daniela Godderz and
R.Jurgen Dohmendoi:10.1038/nature10393Abstract:

basis of PIP2 activation of the classical inward rectifier K+ channel
Kir2.2 pp495-498Scott B.Hansen, Xiao Tao and Roderick

[本来要览](选自United KingdomNature杂志,二〇一一年一月4日问世)封面轶事:
& VIEWS———————-Planetary science: Making mountains out
of a moon pp36-37The Moon’s cratered surface preserves the record of
impacts that occurred during the late stages of its accretion. New
simulations show that a collision with a companion moon may have formed
the lunar farside highlands. See Letter p.69Maria T.
superconductivity: The great quantum conundrum pp37-39Twenty-five years
on from its discovery, high-temperature superconductivity remains
without a satisfactory explanation. The latest studies on the electronic
phase diagram of copper oxide compounds reveal why this is so. See
Letter p.73Paul Michael
Shades of the savannah pp39-40Whether African savannahs had an impact on
the evolution of our early ancestors has been a matter of debate. A
study of carbon isotopes from ancient soils provides fresh clues. See
Article p.51Craig S.
Heat-thirsty bats pp40-41Vampire bats sense infrared radiation to locate
places where blood flows close to their prey’s skin. At a molecular
level, this ability is underpinned by the intricate redesign of an ion
channel on facial nerves. See Letter p..88M. Brock
& 100 years ago
Forecasting the rain ratio pp41-42Marine algae known as coccolithophores
produce much of the ocean’s calcium carbonate. A large survey reveals
how these organisms’ calcification processes and species distribution
change in response to carbon dioxide levels. See Letter p.80David A.
cover and hominin environments in the past 6 million years pp51-56Thure
E. Cerling et al.doi:10.1038/nature10306Abstract:

the growth and form of the gut pp57-62Thierry Savin et

critical role for TCF-1 in T-lineage specification and differentiation
pp63-68Brittany Nicole Weber et al.doi:10.1038/nature10279Abstract:
the lunar farside highlands by accretion of a companion moon pp69-72M.
Jutzi and E. Asphaugdoi:10.1038/nature10289Abstract:

between spin fluctuations and electron pairing in copper oxide
superconductors pp73-75K. Jin et al.doi:10.1038/nature10308Abstract:

in crystals of quantum molecular magnets pp76-79S. Takahashi et

of coccolithophores to carbonate chemistry and ocean acidification
pp80-83L. Beaufort et al.doi:10.1038/nature10295Abstract:

digestive capacity in predators reflects a life of feast and famine
pp84-87Jonathan B. Armstrong and Daniel E.

splicing of TRPV1 underlies infrared sensation in vampire bats
pp88-91Elena O. Gracheva et al.doi:10.1038/nature10245Abstract:

and pupillary light reflex are mediated by distinct populations of
ipRGCs pp92-95S.-K. Chen, T. C. Badea and S.

adaptation to NK-cell-mediated immune pressure pp96-100Galit Alter et

prevents female reprogramming in the postnatal mammalian testis
pp101-104Clinton K. Matson et al.doi:10.1038/nature10239Abstract:

Polycomb-based switch underlying quantitative epigenetic memory
pp105-108Andrew Angel, Jie Song, Caroline Dean and Martin

uncoupling protein 2 structure determined by NMR molecular fragment
searching pp109-113Marcelo J. Berardi, William M. Shih, Stephen C.
Harrison and James J. Choudoi:10.1038/nature10257Abstract:

[自然要览](选自United KingdomNature杂志,二〇一一年12月08日出版)分歧档期的顺序T-细胞的差距化迁移:
& VIEWS———————-Astrophysics: Broad escape from the abyss
pp164-165New ultra-high-resolution images of the radio galaxy M87 show
the origin of a jet very close to the galaxy’s black hole, revealing
that jets start as broad flows before straightening into nearly
cylindrical beams. See Letter p.185Alan P.
When lights take the circuits out pp165-166Circuit-level perturbations
in the brain’s electrical activity may underlie social-interaction
deficits seen in people with schizophrenia and autism. A new optogenetic
tool was instrumental in making this discovery. See Article p.171Joao
Peca and Guoping
Let them eat fat pp166-167A specialist neuron uses an intriguing process
to help control the body’s response to hunger. A lipid pathway involving
the breakdown of cellular components regulates the expression of a
neuropeptide that affects feeding and body weight.Scott M.
& 100 years ago
Earth’s patchy late veneer pp168-169A ‘late veneer’ of meteoritic
material, added after Earth’s core had formed, may be the source of our
noble metals. Its absence from some parts of Earth’s mantle will now
force a rethink about this late accretion. See Letter p.195Thorsten
Let sleeping DNA lie pp169-170In hereditary breast and ovarian cancers
caused by absence of the BRCA1 protein, genomic instability may ensue
from the ‘awakening’ of repetitive DNA sequences in structurally
condensed chromosomal regions. See Article p.179Ashok R.
excitation/inhibition balance in information processing and social
dysfunction pp171-178Ofer Yizhar et al.doi:10.1038/nature10360Abstract:

tumour suppression occurs via heterochromatin-mediated silencing
pp179-184Quan Zhu et al.doi:10.1038/nature10371Abstract:

origin of the radio jet in M87 at the location of the central black hole
pp185-187Kazuhiro Hada et al.doi:10.1038/nature10387Abstract:

classical Cepheid variable stars in the nuclear bulge of the Milky Way
pp188-190Noriyuki Matsunaga et al.doi:10.1038/nature10359Abstract:

charge-stripe order in the high-temperature superconductor YBa2Cu3Oy
pp191-194Tao Wu et al.doi:10.1038/nature10345Abstract:

tungsten isotopic composition of the Earth/’s mantle before the terminal
bombardment pp195-198Matthias Willbold, Tim Elliott and Stephen

plant diversity is needed to maintain ecosystem services pp199-202Forest
Isbell et al.doi:10.1038/nature10282Abstract:

rearrangements maintain a polymorphic supergene controlling butterfly
mimicry pp203-206Mathieu Joron et al.doi:10.1038/nature10341Abstract:

genome sequence of Atlantic cod reveals a unique immune system
pp207-210Bastiaan Star et al.doi:10.1038/nature10342Abstract:

in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and
ALS/dementia pp211-215Han-Xiang Deng et

patterns of peripheral migration by memory CD4+ and CD8+ T cells
pp216-219Thomas Gebhardt et al.doi:10.1038/nature10339Abstract:

clearance of apoptotic cells critically depends on the phagocyte Ucp2
protein pp220-224Daeho Park et al.doi:10.1038/nature10340Abstract:

oxygenase is synthetically lethal with the tumour suppressor fumarate
hydratase pp225-228Christian Frezza et

promotes interleukin-3-independent basophil haematopoiesis and type 2
inflammation pp229-233Mark C. Siracusa et

binding at a [lsqb]4Cu:2S[rsqb] copper-sulphur cluster in nitrous
oxide reductase pp234-237Anja Pomowski, Walter G. Zumft, Peter M. H.
Kroneck and Oliver Einsledoi:10.1038/nature10332Abstract: